 Scaffolds are used in tissue engineering to provide a structure for cells to attach, grow, and differentiate into functional tissues. These structures must meet certain criteria such as mechanical strength, surface characteristics, porosity, degradability, and biocompatibility. In this study, polymeric scaffolds reinforced with electroactive particles were investigated for potential use in bone tissue engineering. The scaffolds were produced using an extrusion-based additive manufacturing system and then modified with varying amounts of pristine graphene. The surface properties and biological responses of these scaffolds were compared and it was found that the addition of pristine graphene led to improved cell viability and proliferation. Additionally, surface modification led to enhanced cell response. This article was authored by Weguang Wang, Guilherme Catano, William Stephen Ambler, and others.