 Throughout history, scientists have strived to understand the miracle of life. They have studied every living thing, exploring deeper and deeper. And the more scientists explore, the more questions they raise, new technologies eventually enable them to capture more biological data than ever. So much data that they could not process it alone. This is where bioinformatics comes into action. A discipline that applies computer and data science to the understanding of biological questions. At SIB, this is what we do. Our team of experts organise, analyse and store the data. We develop ingenious software and methods to interpret data and to make predictions. With our curiosity and passion for biological data, we build essential databases of knowledge used by life scientists all over the planet. On a daily basis, we help scientists in their research to tailor treatments to individual cancer patients or to reveal how chameleons get their colour. We can also predict the geographical spread of epidemics or find out if a fetus has a trisomy at no risk to the mother or the baby. For all these incredible discoveries to happen, our software developers, bioinformaticians and biocurators collaborate hand in hand with life scientists and clinicians. We also train scientists in getting the best bioinformatics skills for their daily work, both in academia and industry. In 20 years, we have become the largest national network of bioinformaticians in Europe and with more data becoming available every day, we will need that brain power more than ever. So we are here and ready to keep on generating and preserving knowledge for the future generations. SIB, 20 years of commitment.