 Noncystic fibrosis bronchiectasis, NCFB, is a common and debilitating condition that can be difficult for patients to manage due to the complexity of their treatment regimen. Poor adherence to these treatments can lead to poorer outcomes such as decreased quality of life, faster progression of lung function decline, and increased risk of recurrent pulmonary exacerbations. There are multiple factors that contribute to non-adherence in NCFB, including difficulty understanding instructions, lack of motivation, and financial constraints. Interventions to improve adherence should focus on addressing these barriers and providing supportive care to help patients better manage their condition. This article was authored by Christina S. Thornton, One Journey Semiogy, and Rachel K. Lim.