 The study presents an efficient z-scheme heterojunction composed of single AG atoms anchored polymeric carbon nitride and SNO2-X for piezo-photocatalysis, which utilizes mechanical energy to modulate spatial and energy distribution of photo-generated charge carriers. The synergy between the single AG atoms and the z-scheme heterojunction initiates a cascade electron transfer from SNO2-X to AGPCN and then to O2 adsorbed on AG, which is further accelerated by ultrasound irradiation. The study shows that the AGPCN slash SNO2-X catalyst efficiently activates O2 into dot O2 minus dot OH and H2O2 under co-excitation of visible light and ultrasound, which are consequently utilized to trigger aerobic degradation of refractory antibiotic pollutants. This article was authored by Wenbin Zhang, Huizhou, Jingyang, and others.