 We've had an art starting, even though they reminded me I of course forgot, we had an art starting yesterday with you know what can we, how can we identify functional elements. We looked in the two application areas that one could consider. One is disease and the other is basic biology. I think in general people try to think of them as a dichotomy like it's a zero sum game if you do one you're going to lose on the other. I hope that the conclusion will come out of this session and considering the previous one is that they actually reinforce each other and that it's a wonderful partnership I think between. Disease is a basic type of biology. It's just one instance of it. So without further ado we'll start with Brenda Andrews who's going to from the University of Toronto who's going to talk about understanding basic biology using functional genomics solving the genotype phenotype problem. Very tad small little thing.