 This study examined the role of Veg-Fe as a potential biomarker for the diagnosis of non-therapeutic, preoperative ovarian cancer patients in comparison with CA-125. Results indicated that serum Veg-Fe levels were significantly lower than those of CA-125 in all stages of ovarian cancer. Furthermore, the highest concentration of serum Veg-Fe was detected in FIGO, International Federation of Gynecology and Obstetrics, which I suggesting its use as one of the diagnostic parameters in the timely investigation of ovarian cancer. This article was authored by Nafisa Mariam, Syed Shoaib Ahmed, Rabayla Lam and others.