 Hello, we are in Warsaw and it's a very hot summer this year and we are eating ice cream and we are eating this ice cream because we got an ignoble prize for medicine this year and we want to tell you a bit what our research is about and you know there is a bone marrow transplantation procedure in medicine and it's a procedure that has many risks. You can die because of sepsis, you can die because of inflammation in your lungs, many bad things can happen and one of them is mucositis. And what is mucositis? Actually, mucositis is a damage to mucosa of our mouth which is done by melphalan. Melphalan is chemo-therapeutic that is given to the patient before the autologous hematopoietic stem cell transplantation. And mucositis is complication, is adverse event of melphalan and to prevent the mucositis that is done by melphalan we decided to give our patient ice cream. Why ice cream? It is known fact that if you cool mucosa you can prevent this complication. Some people use ice cubes but if you think of having an ice cube for two hours in your mouth it's not very convenient for the patient so many centers just don't apply this procedure although we know it works because it's not convenient for the patient and we have this idea that maybe if you just cool down the mucosa and you use it something simple, something that patient actually may like like ice cream you could get the similar effect and what was the effect of just eating few ice creams before or during the chemotherapy? We have shown in our paper that the incidence of oral mucositis in our patients in the group without ice creams was three times higher than in the population with ice cream. So around in the group with ice cream the incidence of oral mucositis was about 20% whereas in the group without ice cream the incidence of oral mucositis was three times higher so about 60%. So what these numbers mean when you think about the transplantation? Think about the Europe. There would be probably around 30,000 transplantation in patients with multiple myeloma. Around 20,000 of these people will get mucositis. If you give them ice cream you can prevent around 10,000 mucositis per year in the patients in Europe alone. It's a big number when you think of it something that you can achieve with very simple means with ice cream. And additionally you shouldn't forget about treatment of complication which is oral mucositis. So for example our patients are given with morphine also total parentera nutrition just because of the oral mucositis. So when you think of that by such an easy way you can prevent oral mucositis in patients prevent also parentera nutrition, morphine it's just like a wrecker for us. Yes. So remember it's not an ignoble thing to give ice cream to prevent mucositis it's actually evidence based medicine. Thank you. Thank you very much. I love you. Love you too. Love y'all. Love you. That was just for Lepe. Mhmm.