Elements S1 • E23

What Is Sickle Cell Anemia and How Do You Get It?





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Published on Feb 27, 2018

This complicated blood disorder affects people from many backgrounds and walks of life, famously including 1 in 400 African-Americans. But how did we discover it in the first place?

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What You Need to Know About Sickle Cell Disease
“Sickle cell disease is an inherited disorder that causes the red blood cells to be abnormally shaped and get stuck inside the blood vessels, making it hard to deliver oxygen throughout the body.”

Who Should Decide If Gene Therapy Is Too Risky, Patients or the FDA?
“Gene therapy is one of those biomedical breakthroughs that has promised to cure Alzheimer’s, cancer, and other disorders for decades. Armed with gene-editing tools like CRISPR, it’s easier than ever to snip out problematic strands of DNA and replace them with new code that deactivates or reverses genetic mutations that cause disease.”

Major ‘Milestone’ Realized in Quest to Transform Stem Cells Into Blood Cells
“Scientists on Wednesday unveiled two methods for coaxing stem cells into blood cells, a long-sought goal that could lead to new treatments for blood disease, including leukemia.”

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