 Five reductase inhibitors have significant outcomes for treating androgenic alopecia but also exert significant side effects in some patients. The literature describes three distinct situations regarding finasteride administration, a compound largely used for AGA, with varying levels of safety and side effects. Factors that may explain finasteride inconsistency should be further investigated to categorize subjects into distinct subgroups. This article was authored by Ion G. Motifei, David L. Rowland, Mewcha Tempa, and others.