 This study examined the epidemiology of stroke in the Gisar region of Tajikistan. Overall, there were 551 cases of stroke recorded over two years, with 65.1% being ischemic, 25.7% hemorrhagic, 3.3% subarachnoid hemorrhage, and 5.9% mixed. Men accounted for 62.3% of the cases, while middle age was most common among those affected. Risk factors included arterial hypertension, long-term psychosocial stress, heart disease, and atherosclerosis. Mortality rates were 0.31 per 1,000 people in 2015 and 0.22 in 2016, depending on the type of stroke. These findings can be used to inform public health policies and improve patient care throughout Tajikistan. This article was authored by M. T. Geneva, T. B. Todd Zidanov, and R. A. Kashimov. We are article.tv, links in the description below.