 Quark-LIG electrochemical sensors fabricated by direct laser writing of natural quark sheets display graphene-like Raman signatures, high conductivity, and fast electron transfer rates. After a 10 minutes electrochemical pretreatment, they can detect tyrosine, tear, in the presence of uric acid, dopamine, ascorbic acid, urea, and glucose with linear detection in the 5 to 150 m range in a LOD of 3.03 m. The sensors also show linear responsive tear in artificial sweat in the relevant physiological range of 5 to 250 micrometers, sensitivity 1.8 times 10 minus 2 a.m minus 1, with LOD of 3.75 micrometers, opening the door to the exploitation of renewable materials such as quark for the development of high quality. Green sensors for health and well-being parameters monitoring. This article was authored by Ewan Vaughn, Chiara Santillo, Michelle Seti, and others.