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Published on Feb 19, 2014
Table of Contents: 00:09 Lecture 3.8: Amperometric Sensors - Glucose Sensors II 00:46 Outline 01:50 Now let us focus on the right 02:50 Glucose sensing 03:18 Michaelis-Menten Equations 08:07 Michaelis-Menten Equation 10:18 Steady-State response: high concentration 12:54 Validation of Glucose response 14:36 Outline 15:29 Let us focus on the diffusion limits 16:35 Bulk amperometry: Glucose/O2 diffusion 17:57 Oxidation-Reaction with Diffusion 19:04 Derive the relationship 21:57 Recall: Diffusion Capacitance 22:50 Recall: Diffusion Capacitance 23:17 Electrode geometry and Amperometric response 26:37 Validation: Experimental results 27:38 Conclusions
This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.