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nanoHUB-U Nanobiosensors L3.8: Sensitivity - Amperometric Sensors - Glucose Sensors II

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Published on Feb 19, 2014

Table of Contents:
00:09 Lecture 3.8: Amperometric Sensors - Glucose Sensors II
00:46 Outline
01:50 Now let us focus on the right
02:50 Glucose sensing
03:18 Michaelis-Menten Equations
08:07 Michaelis-Menten Equation
10:18 Steady-State response: high concentration
12:54 Validation of Glucose response
14:36 Outline
15:29 Let us focus on the diffusion limits
16:35 Bulk amperometry: Glucose/O2 diffusion
17:57 Oxidation-Reaction with Diffusion
19:04 Derive the relationship
21:57 Recall: Diffusion Capacitance
22:50 Recall: Diffusion Capacitance
23:17 Electrode geometry and Amperometric response
26:37 Validation: Experimental results
27:38 Conclusions

This video is part of the nanoHUB-U course "Principles of Electronic Nanobiosensors". (https://nanohub.org/courses/PEN)

This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.

For more details see http://nanohub.org/u

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