 Dookie. Look there. Look at that. What's that? Say hi, buddy. They've missed you. Can I have a kiss, Bubba? Hey Give me a kiss. Give me a kiss Thank you. Thank you, boy What's going on everybody? Raif Derrazy here and today I want to talk about a new HIV Potential HIV vaccine that is going into clinical trials this fall 2020 Get another way that we are working towards ending the HIV epidemic And so let's dive right in there was an article that was published yesterday by the LA Times on the 6th So I'm going to be basically summarizing what this article and what the information from the clinical trial as it's stated on NIH.gov had to say more than 37 million That's 37 million people are living with HIV and get this every single day It is spread to approximately 5,000 new people which amounts to Approximately 1.8 million new transmissions of HIV every year and of those 1.8 million 10% that's a hundred and eighty thousand are newborns. So it's being transmitted from parent to child. In the United States men who have sex with men account for nearly two-thirds of new HIV infections That's a lot And the nearly 25 million transgender people around the world Approximately 50 times more at risk of getting HIV than the general population now in eastern and southern Africa women and girls are 60% of people living with HIV that's six zero sixty percent HIV does not discriminate it is not just a virus that affects the LGBT community as you can tell by those living in eastern and southern Africa it affects large swaths of people and it is something that We are fighting to tackle every day here in the US and around the world And so this new vaccine potential vaccine that's going into clinical trials is yet another avenue from which we can Poke back and say not today HIV Little bit of tidbits about HIV HIV has more genetic diversity than any other Known virus why because as HIV replicates itself, it's not very good at it So it ends up having a lot of mistakes in its genetic coding which are known as mutations so the virus mutates a lot on accident and Regardless of it mutating so much. It's able to survive with the new mutations So every time that happens you're essentially creating a potentially new strain of the virus that is going to Function in a slightly different way. So if you're creating a vaccine that only targets one strain, that's not enough That's not going to cut it because the virus is constantly mutating and creating new strains And we need a vaccine that's going to be able to tackle Multiple large strains of the virus to really have any practical large-scale use Johnson and Johnson is Conducting the large-scale clinical trial and the trial is called mosaic. Oh, so it's like mosaic But with an O at the end their potential vaccine is designed to be effective against multiple strains of HIV And that's exactly what we want the scientists plan to enroll 38 healthy Participants at 50 trial sites located north in South America and in Europe So in North America, it's going to be the US as well as Mexico South America We've got Argentina Brazil Peru and then in Europe Italy Poland and Spain So that's what I was able to see on the NIH website as far as where they're going to have Clinical trial sites if you're interested it's going to be in the fall So you might want to look that up if you want to be a part of that study The study will be a double blind meaning that some of the participants will receive the experimental vaccine while others will receive a placebo and a placebo is basically Nothing it's could be saline water and that's just to ensure that the medicine is actually what is Causing the effects in the participant and not the placebo effect of people thinking that they're receiving treatment And that somehow having an effect on the virus in their body double blind got participants with the experimental vaccine some placebo and also Neither the participants nor the researchers will know who is getting what until the end now I want to reiterate again This is not the only clinical trial that's going on for an experimental vaccine There's for example one in sub-Saharan Africa a similar vaccine is being tested on 2600 women who in that region are the most at-risk population for HIV transmission that trial began in 2017 and The results from that won't be available till minimum 2021 there are also other trials going on in North and South America as well as Africa I want to quote from the LA Times article that researchers with the International AIDS Vaccine Initiative Determined that a vaccine that's 70% effective would do more to prevent new infections than prep So prep is a pill that you can take once a day you take it every day and it prevents HIV transmission by I think 96 to 99% which is amazing It's a huge, you know jump that we've made to be able to do that to offer that to people What they're saying is that if this vaccine is 70% effective It will do more to prevent new HIV transmissions than prep now the mosaic go trial is pushing for 65% effectiveness. That is their specific goal. Being able to have a vaccine Would be an amazing advancement towards ending the HIV epidemic even at 65% efficacy that combined with prep in conjunction with state for sex practices like using condoms also u equals u or Undetectable equals untransmitable for those of us living with HIV when you are on effective treatment and the virus is suppressed in the blood and Considered undetectable for six months or more than you can no longer sexually transmit the virus in our considered Untransmitable so all these things combined with education and stigma reduction access to health care are Going to have an incredible impact on our ability to combat HIV transmissions and the epidemic as we are continuing to work towards a Functional and practical cure for the general population. So that's my little tidbit. I want to share with you guys just another reason for us to continue to have hope and Continue to go about living our lives knowing that HIV is not going to be something that has to Restrict limit or be a source of stigma or hold us back for anything really so I will keep you guys updated Happy New Year. I hope this great news finds you well And I will be in touch soon. Let me know what you guys think as always like this video If you liked it comment below subscribe if you haven't already and I'll see you guys soon. Peace Say goodbye. Say goodbye. Bye. Good boy