 Green tea catechin EGCG has been studied for its health benefits as a nutraceutical agent, but it can also act as a pro-oxidant in certain cellular contexts. Recent research reveals that EGCG directly interacts with proteins and phospholipids in the plasma membrane and regulates various biological processes to exert its beneficial effects. This article was authored by Heisut Kim, Michael J. Kwon, and Jong A. Kim.