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Published on Dec 22, 2017
Join Suzanne Angeli of the Buck Institute on Aging to learn how environmental exposure to manganese is a potential risk factor for developing parkinsonism and Parkinson’s Disease (PD). Occupational exposure to high levels of the element also causes a syndrome known as manganism, which has symptoms very similar to PD. By modeling manganism in a microscopic worm known as C. elegans, Angeli aims to identify new therapeutic interventions to ameliorate the symptoms of PD and other neurodegenerative diseases. Suzanne Angeli grew up in New Orleans, Louisiana. She received her Ph.D. in biomedical sciences from the University of California, San Francisco, where she studied how proteins misfold in neurodegenerative diseases. Currently a postdoctoral researcher at the Buck Institute for Research on Aging, Angeli uses the microscopic nematode, C. elegans, to understand how metals can impact the PD disease state as well as how mitochondria respond to stress and aging. Come be in your elements with Exploratorium host and scientific raconteur Ron Hipschman. Follow tales of intrigue and invention, join in dynamic demonstrations, and uncover fascinating connections between individual elements and our collective human experience.