 2019 NCoV infection has been spreading quickly since its emergence in Wuhan, China, and a deterministic compartmental model was developed to estimate the control reproduction number based on clinical progression, epidemiological status, and intervention measures. The estimations show that interventions such as intensive contact tracing and quarantine can effectively reduce transmission risk, with travel restriction having almost the same effect as increasing quarantine by 100,000 baseline value. Under the most restrictive measures, the outbreak is expected to peak within two weeks with a significant low peak value, and travel restriction can decrease the number of infected individuals in seven days by 91.14% in Beijing compared to no travel restriction scenario. This article was authored by Biao Tang, Xiao Wang, Chen Li, and others.