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Published on Feb 19, 2014
Table of Contents: 00:09 Lecture 2.3: Settling Time - Classical Sensors 00:24 Geometry of diffusion/sensor response 01:03 A 'Mendeleev table' for biosensors 01:46 Outline 02:13 Steady state: analogy to electrostatics 06:47 Diffusion and capture in steady-state 08:10 Time-dependent capture 10:31 Integer dimensional sensors 12:46 Exact solutions in 3D 14:01 Summary: For integer sensors 15:02 Performance limit of biosensors 15:40 Conclusions
This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.