 This paper demonstrates how abstract matrix assisted laser desorption ionization imaging can be used to analyze spatial biology, as well as how it can be applied to identify metabolic channels between glycogen and n-linked glycans. The authors also show how these channels are important for pulmonary fibrosis progression, and they suggest that lysosomal glycogen utilization is necessary for disease development. This article was authored by Lindsay R. Conroy, Harrison A. Clarke, Derek B. Allison, and others.