 A typical hemolytic uremic syndrome, AHUS, is a rare and life-threatening condition characterized by severe kidney damage, low-platelet count, and bleeding problems. It is caused by a dysfunction in the complement system, which is part of the body's immune system. Symptoms may vary depending on the type of AHUS, but typically include fever, fatigue, muscle aches, nausea, vomiting, diarrhea, and skin rashes. Some people also experience headaches, vision changes, and joint pain. AHUS can affect both children and adults, and its severity ranges from mild to life-threatening. Early diagnosis and treatment are essential to prevent further complications. Treatments include plasmapheresis, which removes harmful antibodies from the bloodstream, and the use of medicines such as aculizumab, which blocks the complement system.