 This paper reports on the development of a novel injectable thermosensitive hydrogel composed of poly, anisopropylacrylamide, grafted gelatin, PNIPAMGCS for use in dental tissue engineering. The hydrogel was found to be highly biocompatible and exhibit favorable mechanical properties, allowing it to be used as a scaffold for the growth of human dental pulp stem cells, HDPSCs. Furthermore, the hydrogel was shown to promote osteogenic differentiation of HDPSCs, suggesting its potential application in dental tissue engineering. This article was authored by Mohamed Sami'i, Elahi Dallar Abdallahinia, Nazanin Amiri Agubi, and others.