 Cyclic RGD containing peptide-based compounds with electron withdrawing groups show improved hydrogen bond strength with B.C. lexyl, and compound F with minus 9.2 kcal slash mol is the best dock site in the binding pocket of B.C. lexyl, suggesting potential anti-cancerability. Admet properties were investigated for both compound F and doxorubicin. This article was authored by A.K. Oyubamagi, E.T. Akin Tao, C.O. Akin Tao, and others.