 This study found that chronic periodontitis patients have higher levels of salivary irisin than those who are periodontally healthy. Additionally, it was observed that salivary irisin levels decrease with decreasing plaque percentage in healthy individuals, suggesting that this myokine may be used as a biomarker for chronic periodontal disease. This article was authored by Safiola Khan, Sarah Gaffer, Saba Khaliq and others.