 The NLRP3-inflammacem is a recently discovered component of the innate immune system that plays a critical role in the regulation of inflammation. It is composed of three proteins, NLRP3, ASC, and CASBase-1, and is activated by a variety of stimuli such as bacterial or viral infection, endogenous danger signals, and environmental stressors. Activation of the NLRP3-inflammacem leads to the production of two pro-inflammatory cytokines, interleukin, 1-beta, IL-1-beta, and IL-18, which play important roles in host defense against pathogens and in the development of several autoimmune and inflammatory diseases. Recent studies have shown that targeting the NLRP3-inflammacem may be beneficial for treating these diseases. This article was authored by Bozong Yixiao, Chichi Yisoo, Binzai Yihon, and others. We are article.tv, links in the description below.