 The nucleus, nucleoplasm, first the contents, definition of nucleoplasm, composition of nucleoplasm, and different activities which are taking place in the nucleoplasm. First the definition, nucleoplasm is basically all the soluble portions or molecules which are present within the territory of nuclear envelop. The soluble portion of the nucleoplasm is basically the nucleoplasm. The same is true of cell membranes. The soluble portion of the cell membrane is called cytoplasm, between the nucleus and the cell membrane. Inside the nucleotron, the soluble portion of the nucleus is actually the nucleoplasm. If you imagine what things can happen in the nucleoplasm, let's talk about the composition. First we will see what activities are taking place in the nucleus. There is a DNA in the nucleus. Whenever the DNA is synthesized, nucleotides are required to work in the DNA. This means that already in the nucleoplasm, nucleotides are present in the nucleus. The requirement for energy from this is that ATP is present in the nucleoplasm. RNA molecules are also synthesized in the nucleus. To synthesize the RNA, the ribonucleotides will also be present in the nucleus. Similarly, different enzymes that control the activities in the nucleus will be present in the nucleoplasm. Similarly, when the DNA is packed, the DNA needs histone proteins to be packed. These histone proteins also come into the nucleoplasm by moving from cytoplasm. All these substances are actually ground substances. Ground substances mean that they are stored. When necessary, they will be used there. What are the activities which are taking place in the nucleoplasm? All the activities in the nucleus will be present in the nucleoplasm because the medium of the nucleus is in the nucleoplasm. So, all the activities in the nucleus will be present in the nucleoplasm. For example, there is a DNA replication. So, the replication of DNA is taking place in the nucleoplasm. Similarly, when the RNA is maturation, the nucleoplasm needs to be moved from the nucleus to the cytoplasm. Along with the DNA replication, there is a transcription. During the transcription process, the RNA is formed and the process will also be in the nucleoplasm. In this case, RNA processing. Usually, when the RNA is formed, there is a raw form which has a lot of length and it is not even a protective form. In the nucleus, there is a special process which is called post-transcriptional modification. In post-transcriptional modification, the RNA molecule that is formed is processed. The extra parts are removed. After that, the cap is applied for its protection and the tail is applied. All these activities are called RNA processing. And the work of RNA processing will also be in the nucleoplasm.