Human proteome epitope-level autoantibody profiling service via T7 phage display and immunonprecipitation sequencing:
Sometimes there are advantages to performing antibody surveys with peptides instead of full-length proteins. CDI’s new PhIP-Seq technology synchronizes well with HuProt microarrays by adding broader coverage and epitope-level analysis - making it a strong companion assay to HuProt and an excellent standalone alternative when 3D structure and isotype-specific data are not desired. Our new PhIP-Seq service, developed by CDI’s Scientific Advisory Board Members Steve Elledge and Ben Larman, allows us to analyze patient samples (serum, plasma, CSF, etc.) for the presence of autoantibodies against the full UniProt human proteome.
Human virome epitope-level antiviral antibody profiling service via T7 phage display and immunonprecipitation sequencing:
The collection of viruses found to infect humans (“the human virome”) can have profound effects on health. In addition to directly causing acute or chronic illness, viral infection can alter host immunity in more subtle ways, leaving an indelible footprint on the immune system. Our new VirScan™ service, developed by CDI’s Scientific Advisory Board Members Steve Elledge and Ben Larman, provides an unparalleled way to assay a patient’s viral history by comprehensively analyzing antiviral antibodies to a phage library displaying peptides from 206 species and over 1000 strains of viruses (all viruses annotated to have human tropism in the UniProt database).