Biology: DNA Replication: A Summary





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Uploaded on Jul 29, 2009

http://www.mindbites.com/lesson/1469 for full video.

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In this lesson, Professor Wolfe provides a complete overview of the replication of DNA, beginning with its structure. DNA has a double-helix structure of nucleotides, which made-up of a sugar, a phosphate, and a base. The strands are antiparallel, meaning they run in opposite directions, known as the 5' strand and the 3' strand. DNA replicates by the semi-conservative method of replication.

Professor Wolfe explains how DNA polymerase only reads in one direction, from 3' to 5', and therefore creates ""replication bubbles"" in order to replicate the DNA twice as fast. This creates leading and lagging strands, which require RNA primer and Okazaki fragments added to the lagging strand in order for the process to work properly. At the end of the strands, which lack the free OH molecule needed to complete the process, telomeres are used to protect against a loss of information.

This lesson is perfect for review for a CLEP test, mid-term, final, summer school, or personal growth!

Taught by Professor George Wolfe, this lesson was selected from a broader, comprehensive course, Biology.

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