Vlad's pool: Doesn't break leashes Doesn't get rid of marks.
Put the two together, and is he's got a chains on him, he's pretty much guaranteed to die. E - pools. he loses health, proceed to QRW-ignite to kill. E- attaches. If he pools, it procs anyway, hes stuck. he loses health. Q-R-W ignite to kill. E- attaches. you throw Q - he pools. E still procs. Q doesn't. R-W ignite will still normally kill him - pool costs a fair amount of health. But even if not, safely landing R-W (safely as in, it wont be negated) will allow you to deal a substantial amount of damage - at which point Q-ignite can kill later. E-attaches. Q - lands. whether he pools or not- Chains procs, Q triggers. He's silenced. lost health. R-W ignite. Dead.
Never, ever q-r a vlad if you havent established whether they're slow or not. they;ll just pool through it and proceed to zone you. Never e-q-r either. Risk of pooling is too high. there;s no need to. TAKE YOUR TIME!
Example of taking your time is in 7:25. Q-R wait. Note how he is constantly silenced during this entire period, making him utterly helpless. He walks backs to me because he wants to retaliate - if I hadn't prolonged the silence, there was the risk of taking too much damage.
In this case, i probably would still have lived. But honestly, get into good habits. You dont want to get dived by the jungler for instance. The distort-return was less habit and hoping to juke his ultimate - but he Q'd first for some absurd reason X_x.