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Yamada Lab

  • Cell stretch dependent zyxin recruitment - Duration: 13 seconds.

    • 1 month ago
    • 43 views
    The membrane of MDCK cells expressing zyxin tagged with GFP (right panel, pseudo-colored GFP signal) is stretched using a micro-needle (left panel, phase contrast image). While, in normal condition...
  • Traction force analysis: a migrating cell on a microfabricated pillar array - Duration: 7 seconds.

    • 2 years ago
    • 576 views
    A GFP-integrin beta 1 expressing MDCK cell crawling on a miniature pillar array. The PDMS pillars are soft and deform as migrating cells grab onto the pillar top. The bending pillars are most promi...
  • Microtubule dynamics in live cells - Duration: 18 seconds.

    • 5 years ago
    • 15,092 views
    Dynamic instability of microtubules. GFP-labeled tubulin monomers are constantly assembled at the microtubule tips to elongate the filamentous structure (shown as green), but often rapidly disassem...
  • Blebbistatin enhances membrane extension - Duration: 18 seconds.

    • 5 years ago
    • 3,555 views
    Blebbistatin is a small molecule inhibitor of non-muscle myosin II, which plays a critical role in cell migration, cell division, and many other cellular processes. The sudden inactivation of myosi...
  • Keratinocyte migration - Duration: 8 seconds.

    • 5 years ago
    • 7,946 views
    Cell migration of primary keratinocytes before and after calcium switch. The concentration of calcium was increased from low to high (HC) after 2 hours of imaging. After the calcium switch, the ma...
  • Mammary epithelial cells in a three dimensional matrix - Duration: 15 seconds.

    • 7 years ago
    • 3,878 views
    This video illustrates how human mammary epithelial cells interact with each other and move within a three-dimensional matrix.

    [Imaged by Adrienne Cheung]
  • Interactions between fibroblasts and epithelial cells - Duration: 27 seconds.

    • 7 years ago
    • 16,679 views
    Two completely different kind of cells are moving around on a glass slide. Can you tell which cells are which?
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