yt:channel:UCEaDysGwlId0-wfcIxKjotA UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2010-06-21T13:12:09+00:00 yt:video:MMuFlSH1ANc MMuFlSH1ANc UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2014-01-08T16:15:29+00:00 2017-01-09T17:53:15+00:00 NCI-Designated Cancer Centers: Partners in Advancing Research The NCI-designated cancer centers deliver cutting-edge cancer treatments to patients in communities across the United States. In this video, Dr. Harold Varmus, director of the NCI, and Dr. Linda Weiss, director of the Office of Cancer Centers explain the significance of being an NCI-designated cancer center, as well as the importance of partnering to advance research. Mayo Clinic Cancer Center and Winship Cancer Institute of Emory University are highlighted to show how their research programs promote collaborative research between basic, laboratory, clinical, and population sciences. To learn more about the NCI-designated Cancer Centers, visit http://www.cancer.gov/researchandfunding/extramural/cancercenters. To learn more about NCI's Office of Cancer Centers, visit http://cancercenters.cancer.gov/. yt:video:ABfvbH0YKN4 ABfvbH0YKN4 UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2012-12-13T18:59:29+00:00 2017-01-09T17:54:50+00:00 NCI Partnership Opportunities: Teaming to Bring Better Cancer Tools to Market Researchers at the Center for Cancer Research (CCR), part of the National Cancer Institute, integrate basic and clinical research discoveries into better strategies to detect cancer earlier, diagnose it more precisely, and treat it more intelligently. Our inventions include research tools, therapies, and diagnostics. We have numerous inventions available for licensing, as well as opportunities for collaboration with public and private institutions. These relationships accelerate our innovations to the marketplace for the benefits of public health. Two examples of our innovations are highlighted in this video. To learn more about CCR, please visit the website, http://ccr.cancer.gov. To learn more about the research technologies available at the NCI, visit NCI's Technology Transfer Center website, http://ttc.nci.nih.gov/index.php or NIH's OTT website, http://www.ott.nih.gov. yt:video:XxdGemq8BFI XxdGemq8BFI UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-12-21T14:28:19+00:00 2017-06-19T08:50:16+00:00 Moving Forward: Biospecimens and Cancer Research Biospecimens are materials taken from the human body, such as tissue, blood, plasma, and urine that can be used for cancer diagnosis and analysis. Doctors and researchers may analyze biospecimens to look for indications of disease in the donor. Biospecimens can confirm whether a disease is present or absent in a particular patient. They also provide other information that may be useful to the physician or a researcher. Each sample may contain DNA, proteins, and other molecules important for understanding disease progression. Biorepositories (or biobanks) are "libraries" where biospecimens are stored and made available for scientists to study for clinical or research purposes. These biospecimens are commonly annotated with information about the patient from whom the biospecimen was taken, including data about their medical conditions and background. There are thousands of biorepositories in the United States, which vary widely by size, the type of biospecimens collected, and purpose. This video explains the the critical importance of biospecimens and biorepositories in cancer research and presents perspectives from cancer patients and survivors, doctors who treat cancer patients (oncologists), researchers as well as drug developers. The lack of standardized, high-quality biospecimens is widely recognized as a significant roadblock to cancer research. The National Cancer Institute (NCI), through its Office of Biorepositories and Biospecimen Research (OBBR), is leading a national initiative to systematically address and resolve challenges posted by the limited availability of carefully collected and controlled, high-quality human biospecimens annotated with essential clinical data and properly consented for broad investigational use. OBBR works to support development of a common biorepository infrastructure that promotes resource sharing and team science, in order to facilitate multi-institutional, high throughput genomic and proteomic studies. yt:video:dQ-IlSUq0EQ dQ-IlSUq0EQ UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-08-12T14:55:38+00:00 2017-06-19T08:50:16+00:00 Insights from Genome-Wide Association Studies and the Steps Beyond (highlights) Dr. Stephen Chanock, M.D., Chief of the Laboratory of Translational Genomics in the Division of Cancer Epidemiology and Genetics, discusses insights from cancer genome-wide association studies and the steps beyond. Explore the genomic approaches used in identifying and characterizing cancer susceptibility regions in the human genome, and future trends in this research. This seminar was presented at the Hefei 2011 GWAS workshop in Anhui, China, and was supported by Nature Genetics and by Anhui Medical University. (These are highlights; for the full lecture, go to: http://www.dceg.cancer.gov/ltg/multimedia ) yt:video:GRkJ1z24fAw GRkJ1z24fAw UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-07-13T21:40:40+00:00 2017-06-19T08:50:16+00:00 Camera on Cancer Research: Using Receptor Biology to Understand the Complexities of Cancer Dr. Gordon Hager, Chief of CCR's Laboratory of Receptor Biology and Gene Expression, takes you into his lab where he researches nuclear hormone receptors and their role in modulating the chromatin structure in gene regulation. Watch and listen as Dr. Hager uses living cell technology to better understand the molecular detail of how these processes take place. Learn more about Dr. Hager's research at http://ccr.cancer.gov/staff/staff.asp?profileid=5817 yt:video:nzmxwgWQRPs nzmxwgWQRPs UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-07-12T18:47:21+00:00 2017-06-19T08:50:16+00:00 Camera on Cancer Research: Hsp90 Inhibitors, Powerful Drugs in the Fight Against Cancer Dr. Len Neckers, Senior Investigator in CCR's Urologic Oncology Branch, takes you into his lab where he researches the role of chaperone proteins in signal transduction. Dr. Neckers studies the chaperone Hsp90, and has over the years developed Hsp90 inhibitors as novel anti-cancer agents. Watch and listen to Dr. Neckers' progress in developing the next generation of Hsp90 inhibitors to be used as powerful drugs in the fight against cancer. Learn more about Dr. Neckers' research at http://ccr.cancer.gov/staff/staff.asp?profileid=5712 yt:video:QmNncxWU3U0 QmNncxWU3U0 UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-07-12T18:25:37+00:00 2017-06-19T08:50:16+00:00 Camera on Cancer Research: Helping Fight Metastatic Prostate Cancer Dr. Kathleen Kelly, Branch Chief of CCR's Cell and Cancer Biology Branch, takes you into her lab where she researches the biology and origin of metastatic prostate cancer cells. Watch and listen to Dr. Kelly as she explains her interest in better understanding the signaling pathways that mediate cancer progression and metastasis. Learn more about Dr. Kelly's research at http://ccr.cancer.gov/staff/staff.asp?profileid=5698 yt:video:VdT72zByYpk VdT72zByYpk UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-04-25T14:21:12+00:00 2017-06-19T08:50:16+00:00 Teaming Up to Fight Cancer Dr. Carole Parent, Senior Investigator of CCR's Laboratory of Cellular and Molecular Biology discusses the 2010 signing of the Graduate Partnership Program in Cancer Technology. This agreement allows Dr. Parent and other NCI researchers to collaborate with University of Maryland students studying physics and math in hopes of encouraging groundbreaking cancer research. In the video, you will meet University of Maryland physics student Colin McCann, who is currently collaborating with Dr. Parent. Learn more about Dr. Parent's research at: http://ccr.cancer.gov/staff/staff.asp?profileid=5631 Read about the NCI/UMD collaboration in CCR Connections at: http://home.ccr.cancer.gov/connections/2010/Vol4_No2/news_9.asp yt:video:9OGJuSVbh5E 9OGJuSVbh5E UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-03-17T16:07:07+00:00 2017-06-19T08:50:16+00:00 Camera on Cancer Research: Using a Cancer Vaccine to Provide Hope Dr. James Gulley, Director of CCR's Clinical Immunotherapy Group, takes you into his clinic where he plans and conducts numerous clinical trials using cancer vaccines to treat and prevent cancer. You will hear from three of Dr. Gulley's patients currently enrolled in his clinical trials. While each patient shares their story, you will get a better understanding of the drive and passion behind Dr. Gulley's research. Learn more about Dr. Gulley's research at http://ccr.cancer.gov/staff/staff.asp?profileid=5686 yt:video:utE_HdAdDQw utE_HdAdDQw UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-02-25T14:56:56+00:00 2017-06-19T08:50:16+00:00 The Cancer Genome Atlas: The Genetic Basis of Cancer This video is one in a series of videos from The Cancer Genome Atlas (TCGA) project, explaining TCGA's approach to determining the important genomic changes that lead to cancer. TCGA researchers, Drs. Richard Gibbs, Peter Laird, Stacey Gabriel and Neil Hayes, talk about the difference between a normal cell and cancer cell and how understanding the changes in DNA that cause cancer can help doctors develop better treatments. The Cancer Genome Atlas is a comprehensive and coordinated effort supported by the National Cancer Institute and the National Human Genome Research Institute to accelerate our understanding of the genetics of cancer using innovative genome analysis technologies. To learn more about The Genetic Basis of Cancer, please visit http://cancergenome.nih.gov/newsevents/multimedialibrary/videos/thegeneticbasisofcancer yt:video:VyKns0LhduY VyKns0LhduY UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-02-23T15:26:29+00:00 2017-06-19T08:50:16+00:00 Neuro-Oncology Branch, Brain Tumor Clinic This video introduces the Neuro-Oncology Branch (NOB), a trans-institutional program of the National Cancer Institute and the National Institutes of Neurological Disorder and Stroke of the NIH. The NOB constitutes a team of dedicated medical professionals and scientists working to uncover new discoveries underlying the genetics and biology of brain tumors and to translate those findings to the development of exciting and meaningful new treatments for patients afflicted with these tumors. Administration of these new treatments through clinical trials, optimal state of the art standard therapy and patient consultation are offered to patients throughout the United States free of charge through the coordinated, multidisciplinary approach to patient care in the NOB's Brain Tumor Clinic. Learn more about the Neuro-Oncology Branch and the Brain Tumor Clinic at http://home.ccr.cancer.gov/nob/default.asp yt:video:KSQd63PQEiE KSQd63PQEiE UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-01-28T19:11:06+00:00 2017-06-19T08:50:16+00:00 The Cancer Genome Atlas: The Value of DNA Sequencing This video is one in a series of videos from The Cancer Genome Atlas (TCGA) project explaining TCGA's approach to determining the important genomic changes that lead to cancer. TCGA researchers, Drs. Richard Gibbs, Lynda Chin, Stacey Gabriel and Paul Spellman, explain DNA sequencing and what it tells us about DNA changes in cancer, how looking across many tumors will help us to find which changes are meaningful and identify potential drug targets, and how genomics is changing how we think about cancer. The Cancer Genome Atlas is a comprehensive and coordinated effort supported by the National Cancer Institute and the National Human Genome Research Institute to accelerate our understanding of the genetics of cancer using innovative genome analysis technologies. To learn more about The Value of DNA Sequencing, please visit http://cancergenome.nih.gov/newsevents/multimedialibrary/videos/dnasequencing yt:video:_CB80lR0pmQ _CB80lR0pmQ UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-01-28T19:04:25+00:00 2017-06-19T08:50:16+00:00 The Cancer Genome Atlas: The Role of Tumor Samples in TCGA This video is one in a series of videos from The Cancer Genome Atlas (TCGA) project, explaining TCGA's approach to determining the important genomic changes that lead to cancer. TCGA researchers, Drs. Marsten Linehan, Neil Hayes, and Julie Gastier-Foster, explain the role of tissue samples in cancer research and TCGA, the importance of quality biospecimens, and the stringent quality control upheld by TCGA to ensure robust research results. The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort supported by the National Cancer Institute and the National Human Genome Research Institute to accelerate our understanding of the genetics of cancer using innovative genome analysis technologies. To learn more about The Role of Tumor Samples in TCGA, please visit http://cancergenome.nih.gov/newsevents/multimedialibrary/videos/tumorsamples yt:video:uU9fQ5oPIA8 uU9fQ5oPIA8 UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-01-28T19:02:11+00:00 2017-06-19T08:50:16+00:00 The Cancer Genome Atlas: The Power of TCGA Data This video is one in a series of videos from The Cancer Genome Atlas (TCGA) project, explaining TCGA's approach to determining the important genomic changes that lead to cancer. TCGA researchers, Drs. Joe Gray, Chris Sander, Doug Levine and Richard Gibbs explain how TCGA is set up to collect and share genomic data, the importance of bioinformatics in sifting through the data to find important features, and how TCGA is changing the way we think of cancer. The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort supported by the National Cancer Institute and the National Human Genome Research Institute to accelerate our understanding of the genetics of cancer using innovative genome analysis technologies. To learn more about The Power of TCGA Data, please visit http://cancergenome.nih.gov/newsevents/multimedialibrary/videos/thepoweroftcgadata yt:video:epsZjJ_A1y4 epsZjJ_A1y4 UCEaDysGwlId0-wfcIxKjotA NCIresearchfunding https://www.youtube.com/channel/UCEaDysGwlId0-wfcIxKjotA 2011-01-28T18:52:07+00:00 2017-06-19T08:50:16+00:00 The Cancer Genome Atlas: The Link Between TCGA and Personalized Cancer Therapies This video is one in a series of videos from The Cancer Genome Atlas (TCGA) project, explaining TCGA's approach to determining the important genomic changes that lead to cancer. TCGA researchers, Drs. Joe Gray, Neil Hayes, Doug Levine, Lynda Chin and Marsten Linehan, explains how genomics has changed the direction of cancer research with the understanding that even cancers from the same anatomical site such as breast cancer are often genomically different and that knowing the genomic defect in an individual's cancer can help doctors tailor or personalize their treatment based on this information. The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort supported by the National Cancer Institute and the National Human Genome Research Institute to accelerate our understanding of the genetics of cancer using innovative genome analysis technologies. To learn more about The Link Between TCGA and Personalized Cancer Therapies, please visit http://cancergenome.nih.gov/newsevents/multimedialibrary/videos/personalizedcancertherapies