Food manufacturers regularly use glass containers for a wide range of applications, including infant foods, cooking sauces, condiments, vegetables and pickles, beverages, and oils and dressings, to name just a few. Despite its popularity, glass packaging poses a significant safety risk and the effects of glass-in-glass contamination can be highly damaging. A tiny fragment of glass can cause serious injury to a consumer, and the subsequent adverse publicity (particularly if a baby or child was severely cut), combined with the high cost of product recalls, can have a devastating impact on a business. Selecting the right x-ray inspection system is fundamental to guaranteeing optimum glass-in-glass detection. X-ray inspection equipment cannot solve contamination problems unless each element – from beam angle to reject mechanism – has been chosen to fit the line and the product. We will discuss the factors affecting glass in glass detection capability and provide insight to selecting the proper solution.