Virus Is Found in Many With Chronic Fatigue Syndrome

Loading...

Sign in or sign up now!
Alert icon
Upgrade to the latest Flash Player for improved playback performance. Upgrade now or more info.
2,121
Loading...
Alert icon
Sign in or sign up now!
Alert icon

Uploaded by on Oct 10, 2009

Virus Is Found in Many With Chronic Fatigue Syndrome

Many people with chronic fatigue syndrome are infected with a little known virus that may cause or at least contribute to their illness, researchers are reporting.

The syndrome, which causes prolonged and severe fatigue, body aches and other symptoms, has long been a mystery ailment, and patients have sometimes been suspected of malingering or having psychiatric problems rather than genuine physical ones. Worldwide, 17 million people have the syndrome, including at least one million Americans.

An article published online Thursday in the journal Science reports that 68 of 101 patients with the syndrome, or 67 percent, were infected with an infectious virus, xenotropic murine leukemia virus-related virus, or XMRV. By contrast, only 3.7 percent of 218 healthy people were infected. Continuing work after the paper was published has found the virus in nearly 98 percent of about 300 patients with the syndrome, said Dr. Judy A. Mikovits, the lead author of the paper.

XMRV is a retrovirus, a member of the same family of viruses as the AIDS virus. These viruses carry their genetic information in RNA rather than DNA, and they insert themselves into their hosts genetic material and stay for life.

Dr. Mikovits and other scientists cautioned that they had not yet proved that the virus causes the syndrome. In theory, people with the syndrome may have some other, underlying health problem that makes them prone to being infected by the virus, which could be just a bystander. More studies are needed to explain the connection.

But Dr. Mikovits said she thought the virus would turn out to be the cause, not just of chronic fatigue, but of other illnesses as well. Previous studies have found it in cells taken from prostate cancers.

I think this establishes what had always been considered a psychiatric disease as an infectious disease, said Dr. Mikovits, who is research director at the Whittemore Peterson Institute in Reno, a nonprofit center created by the parents of a woman who has a severe case of the syndrome. Her co-authors include scientists from the National Cancer Institute and the Cleveland Clinic.

Dr. Mikovits said she and her colleagues were drawing up plans to test antiretroviral drugs — some of the same ones used to treat HIV infection — to see whether they could help patients with chronic fatigue. If the drugs work, that will help prove that the virus is causing the illness. She said patients and doctors should wait for the studies to be finished before trying the drugs.

Dr. William Schaffner, an infectious disease expert at Vanderbilt University, said the discovery was exciting and made sense.

My first reaction is, At last, Dr. Schaffner said. In interacting with patients with chronic fatigue syndrome, you get the distinct impression that theres got to be something there.

He said the illness is intensely frustrating to doctors because it is not understood, there is no effective treatment and many patients are sick for a long time.

He added, This is going to create an avalanche of subsequent studies.

  • likes, 0 dislikes

Link to this comment:

Share to:
see all

All Comments (3)

Sign In or Sign Up now to post a comment!
  • Wow, three other symtoms were mentioned. Before casting the news PLEASE do your research. The name of CFS was altered from the originally named illness of M.E., Myalgic Encephalomyelitis. When it was altered to focus on only fatigue and the three mentioned symptoms research slowed to a dull pace and funding minimized as a non important illness.This illness was originally called and is still called M.E., which has over 60 symptoms and effects the neurological system, immune system and endocrine.

  • Looks like it causes chronic yawning too...if only.

    These news pieces should try showing some real pictures of sick people with CFS/ME not actors yawning and snuggling down on the settee for a nap. People who have not worked in more than a decade and have no life and no friends and are disabled. People like me.

Loading...

Alert icon
0 / 00Unsaved Playlist Return to active list
    1. Your queue is empty. Add videos to your queue using this button:
      or sign in to load a different list.
    Loading...Loading...Saving...
    • Clear all videos from this list
    • Learn more