Vaccine Safety Conference Session 20 - Dr. Richard Deth, PhD

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Uploaded by on Oct 20, 2011

Dr. Richard Deth, PhD Oxidation and Methylation in Human Brain: From Autism to Alzheimer's

Dr. Richard Deth is Professor of Pharmacology in the Department of Pharmaceutical Sciences at Northeastern University where he has held a faculty appointment since 1976 and where he has served as Department Chairman and Director of the Pharmacy Program Director. He received his BSc degree in Pharmacy from State University of New York at Buffalo and his doctoral degree in Pharmacology from the University of Miami. His research interests are focused on the role of impaired methylation reactions in neurodevelopmental and neurodegenerative disorders, including the important influence of oxidative stress.

His earlier research involved studies of receptor-initiated G-protein activation and second messenger formation. Subsequently he identified the unique ability of the D4 dopamine receptor to carry out phospholipid methylation and showed that numerous environmentally-derived toxins, including heavy metals, potently impair this process. In recent years his work has focused specifically on autism, helping to understand the causes contributing to the current "autism epidemic", and identifying novel treatments. He has testified before Congress and in vaccine court proceedings about how mercury-containing vaccine preservatives might contribute to rising autism rates. Deth is the author of Molecular Origins of Human Attention: The Dopamine-Folate Connection, a book that provides a useful framework for understanding the role of D4 receptor-mediated methylation in neuropsychiatric disorders.

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  • I like the pronunciation better than the spelling.

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