Uploaded by ALMARJAT on Oct 8, 2008
حلقة عن مرض crom syndrome أما crom disease مع مجموعه من أسئله المشاهدين والرد عليهم مع الدكتور رالف عيراني أخصائي تغذية وطب تجانسي A disease crom syndrome The crom disease with a range of questions from the audience and respond to them with Dr. الصحه التغذية مع الدكتور رالف عيراني الفيتامين b In recent years, the value of genetic testing has increased for the diagnosis of various
The role of cytogenetics has grown since the discovery of trisomy 21 in Down syndrome and monosomy X in Turner syndrome nearly 40 years ago. Chromosome abnormalities have been associated with birth defects, mental retardation, infertility, pregnancy loss, hematologic disease and cancer. Prenatal cytogenetic analysis has become the standard of care for those patients at increased risk because of advanced maternal age, abnormal maternal serum screen, abnormal ultrasound findings, or a family history of birth defects. Many characteristic chromosome abnormalities have been associated with specific hematologic diseases and their identification provides prognostic and diagnostic information. Molecular cytogenetic techniques, especially fluorescent in situ hybridzation (FISH), have become an important adjunct to classical cytogenetics. Several chromosomal syndromes (e.g. Williams, Miller-Dieker and DiGeorge/ Velocardiofacial syndromes) have been identified that are at or beyond the limits of standard chromosome methods, and diagnosis is incomplete without both karyotype analysis and specific FISH assays. Using DNA probes, FISH allows for more sensitive and specific identification of gene sequences in interphase and metaphase cells.
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