Ibuprofen Can Interfere with Aspirin's Antiplatelet Effect

FDA is alerting healthcare professionals that taking 400 mg of ibuprofen can interfere with the antiplatelet effect of low dose aspirin i.e., the 81 mg of aspirin per day taken by many patients for its cardioprotective effect. Because of this interference, FDA suggests that you advise patients who use both immediate-release, low-dose aspirin and ibuprofen at the 400 mg strength to take the ibuprofen at least 30 minutes after the aspirin, or at least 8 hours before the aspirin.

This is most important for those patients who use the ibuprofen on a regular basis. Occasional use of ibuprofen is not likely to alter the cardioprotective effect of aspirin significantly. You should also assume that other nonselective OTC NSAIDs can interfere with the cardioprotective effect of low-dose aspirin unless proven otherwise. It is not certain at this point whether ibuprofen doses greater or less than 400 mg can interfere with the cardioprotective effect of low-dose aspirin.

Category:

News & Politics

Tags:

• Ibuprofen
• Aspirin
• Antiplatelet
• FDA
• Cardioprotective
• Patient
• Safety

[XxDrD34THxX]

ima take 2 right now they tied my braces tighter than normal... i dnt take it like crazy tho... like once every 3 mo