Total synthesis of lysergic acid

An overview of the 1956 total synthesis of lysergic acid, the product of which is one step away from LSD. A lot of "classical" methods, and one reaction that would involve some interesting health & safety paperwork. DOI: 10.1021/ja01594a039

Category:

Science & Technology

Tags:

• chemistry
• LSD

[collectivemind513]

oh and the video is 4:20

[AMAgostini]

No one appreciates the actual organic chemistry you just showed us. Impressive and easy to follow (With sufficient organic knowledge).

[clarkewi]

Is this supposed to be a "simple" and "safe" method?

[367c]

so... i can do this in my bathtub right?

[aeroscope]

Holy crap can you speak slower?!?!?

[stk931]

@phunkyjunkee hahah evrbody who goes to phish shows does lsd

[phunkyjunkee]

I think more good chemists should make LSD if this is really the way... Use it to treat drug addiction, for relationship counceling, depression, boredom, anything really... I love to do it at Phish shows! LOL

[shambrawk]

you should make a series of these in SLOOOOOOOW MOOOOOTION, so I can at least memorize it, if not yet understand it.

[palmerfricks92]

@Humanfromd1 What are you talking about d00d "acid" is the streetname for lsd

[Falco365]

I love you.