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biosights: December 26, 2011 - A Twin-Track Approach to Building Desmosomes

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Uploaded by on Jan 9, 2012

Desmosomes are intercellular adhesions whose adhesive core is formed by two distinct classes of cadherin molecules -- desmogleins and desmocollins. Nekrasova et al. reveal that these two cadherins are independently transported to the cell surface by two different kinesin motors. This biosights episode presents the paper by Nekrasova et al. from the December 26, 2011, issue of The Journal of Cell Biology and includes an interview with senior author Kathleen Green (Northwestern University Feinberg School of Medicine, Chicago, IL). Produced by Caitlin Sedwick and Ben Short.

Read the related article online at: http://jcb.rupress.org/content/early/2011/12/14/jcb.201106057.full

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