Mayo Clinic Study on Radiation Risks of Angioplasty

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Uploaded by on Mar 15, 2010

Body size, gender and the complexity of heart disease significantly influence how much cumulative radiation skin dose that patients receive during percutaneous coronary intervention (PCI) therapy, also known as angioplasty, according to a new Mayo Clinic study. The study was undertaken as a quality control initiative to reduce the potential radiation risks of cancer to patients and PCI operators. Presented today at the annual meeting of the American College of Cardiology, the review of 14 months worth of radiation data from 1,827 adult patients is an important early step in understanding ways to improve PCI safety and quality while optimizing therapeutic benefits. The Mayo Clinic study identified 20 clinical traits and circumstances that help predict whether a patient likely received higher or lower doses of radiation. Significance Identifying optimal means of using radiation in PCI is important because a chief advantage of PCI is its minimally-invasive nature in successfully opening vessels and placing stents, which makes it an increasingly popular option for treating select cases of heart disease. PCIs minimally-invasive advantages include reducing patient trauma, speeding recovery and lowering costs, compared to traditional heart surgeries. However, PCI owes its precision, safety and effectiveness to the X-ray fluoroscopy imaging used. X-ray fluoroscopy produces many images to make a movie that allows physicians to visualize the intricate vessel anatomy being treated and, therefore, holds the potential for increased radiation risk. The amount of radiation dose used during PCI procedures is generally much greater than that used for a typical X-ray image such as a chest X-ray. But because a chest X-ray is usually a screening test and a PCI is a lifesaving procedure, from the clinical perspective, the risk of not performing the PCI is much greater than the predicted radiation risk associated with the procedure. Mayo study results show: •Indicators of higher radiation dose included male gender higher body mass index (BMI); more complex disease, such as multiple diseased vessels or complex anatomy and lesions in the vessels; and previous history of coronary artery bypass graft (CABG) surgery. •The median patient Body Mass Index (BMI) was 29.7, with most patients having a BMI between 21 and 44.6. A BMI less than 30 can fall into normal (2024.9) or overweight (2529.9) categories. •The median cumulative skin radiation dose was 1.5 Gray (Gy), a unit of absorbed radiation, with a range 0.34 Gy to 4.5 Gy. In general, the cancer risk for a typical PCI is likely about 0.05 percent, whereas the natural cancer rate from daily living is about 35 percent, the Mayo team noted. Implications for Cure Radiation risk is a recognized hazard of our specialty that has not been systematically or aggressively addressed, explained Chet Rihal, M.D., lead cardiovascular physician on the study. But our commitment to patient safety and quality at Mayo Clinic, and to protecting operators who perform the therapy, makes this a priority issue for us. The next step for us is to follow up from this initial identification of the problem and lead efforts to formulate specific practice changes clinicians can use to improve safety while maintaining quality. Data also showed that radiation doses that comparable patients received differed depending on which of the 13 physicians treated them. Dr. Rihal said investigating possible causes of this finding is among the goals of the next phase of study. In this video, Dr. Rihal talks about the study, it's findings and what it means.

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  • the best start is to burn the ncrp report #147, revert back to ncrp report 49 and use ncrp report 116 for dose rate models. Id love to see this docs face with my fluke 451p meter showing how little the piss poor shielding he is putting his faith into. 90% of the current radiology rooms are not shielded to safe dose levels, no wonder they are affraid to do leakage surveys in these depts nevermind take the time to do a basic workload calculation.

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