Complement Cascade LOL

When everyone in lecture first watched this video, and saw what we had to memorize, the response went from boredom to nervous laughter to loud laughter back to scared laughter to dead silence.

For the non-Immunology-students:

Your body has a magical rainbow Tic-Tac brigade that can stab bacteria to death. These Tic-Tacs have annoyingly long names that really aren't necessary.

Also, the Tic-Tac brigade can't begin it's killing rampage until the magical octopus molecule first says "O HAI BACTERIA WANNA B FRIENDS? LEMME JUST GIVE U A FRIENDLY LITTLE HUG... J/K J/K LULZ!!11!! YOU GONNA GET PWNED!!!"

Category:

Science & Technology

Tags:

• immunology
• complement
• cascade

[EmmVeePeePBN]

Haha, we had a similar video in my immunology class, with the exact same reaction.

PennState with Dr. Mastro by any chance?

[CitrusCat]

I'm afraid not, this was at the University of Colorado in Boulder with Dr. Fleshner. But I think that the videos in that Immunobiology text have a sort of universal effect on college students nationwide. :)

Did you take immunology recently? I took it last spring semester and watching this now, it's amazing how much of that class never made it past my hippocampus. Good thing I kept the book + CD to review before I apply to any grad schools.

[KulaAShaker]

This is very important. Each C1 molecule needs two of its globular heads to be bound (an antibody each) for it to be actiivated. If there is only one C1q molecule (therefore one globular head) how can the C1 molecule be activated and thus continue the cascade?

[CitrusCat]

Sorry to inform you that I am by no means an expert in immunology, merely an undergrad that was amused by the "intensity" of this video. I'm sure that if you spotted a mistake it could very well be there, but panicking on my comments won't get you anywhere. :P Try talking to a professor instead.

[naseerahvj]

LMAO!!!! That is the best discription ever! I'm a Medicaal lab student and when I first got my clinical books I went from, "this is soo cool" to "OMG I have 2 years to memorize all this before my cirtification exam!"

[tishwalter]

I lolled at the description. So glad I only need to know the vague way this works.

[CitaL0v3]

We had a similar video in microbiology... same thing happened... nervous laughter, obnoxious laughter, nervous laughter and silence. lol too funny

[ShogunPJ]

We were shown this in our lectures to, same response from the UK hah

[sautjansurarrusinur]

Hahaha!

[cat1edinburgh]

Ooh I just saw this in a lecture today :) Need something to help..!

[BlitzHeavyMetal]

It's been a year since Immunology and I still love the complement cascade.. And then they teach it again as a seminar for us medtech seniors. And i forgot everything again..

[avista100]

OMG at first i thought you were from my class, but you r from the us and I'm from the UK..... THIS VIDEO WAS PLAYED TO OUR YEAR GROUP ASWELL.... AND WE DID THE EXACT SAME THING... EXCEPT ALL ~300 OF US STARTED LAUGHING DURING THE VIDEO WHEN IT STARTED SOUNDING RIDICULOUS ... lol the lecturer laughed and then told us to pay attention and played it again. LOL

[chungmaster2332]

This was my favorite video from Immunology class. When I first saw it, I was baffled by it. But now everything makes sense.

[fury17deco]

I am taking an Immunology and Serology exam on complement this morning as part of an MLT program. For some reason, I haven't had as much trouble understanding complement as my fellow students. This was a good graphical representation of the classic pathway. Do you also have video of the alternate and manose binding lectic pathways?