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Serious Muscle Injury with Statins

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Uploaded by on Dec 12, 2008

FDA is reminding healthcare professionals that patients who take amiodarone along with drugs that contain simvastatin have an increased risk of rhabdomyolysis, a type of muscle injury that can lead to kidney failure and death. Amiodarone is an antiarrhythmic drug and simvastatin (found in Zocor, Vytorin and Simcor) is used to lower cholesterol.

This increased risk has been described in the labeling for both amiodarone and simvastatin since 2002, but FDA continues to receive reports of rhabdomyolysis in patients treated concurrently with these two drugs, especially when the simvastatin dose is greater than 20 mg per day. Prescribers should avoid doses of simvastatin greater than 20 mg per day in patients who are also taking amiodarone.

When patients start taking simvastatin or their dose is increased, they should be told about the risk of rhabdomyolysis and advised to promptly report any unexplained muscle pain, tenderness or weakness.

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  • My sister is in the hospital right now on life support because of statins. Statins are a big pharma homicide program pure and simple

  • @calvertjason1 I had 87,000 it was so much fun. 5 days in the hospital

  • @calvertjason1 i had it to,very painful.i got mine by to much exercise and a lack of fluids.you wont mind to tell me how your rhabdo happened.,,,just curious.

  • I had rhabdo and it sucked so bad my enzymes jumped to over 42000 and the normal level is like 100

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