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Stem Cells and the End of Aging Part 6 of 6

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Uploaded by on Apr 25, 2007

This lecture, by Dr. Nadia Rosenthal, discusses the role of stem cells in the regeneration and repair of tissues, and their possible medicinal application through the harnessing of their regenerative properties.

HHMI description:
Human tissues vary in their ability to heal and regenerate. The nervous system has weak powers of regeneration, while the skin is quick to make new cells for repair. Mammalian muscle cells are intermediate in their ability to regenerate. Human muscle can regenerate in response to minor wounds and normal wear and tear, but humans will not grow a new bicep, for example, in response to amputation. The heart is the most important muscle in the body and yet has feeble regenerative capabilities. Research into the wholesale production of new replacement organs and limbs is in its infancy, but research into enhancing normal levels of regeneration is progressing rapidly. Recent discoveries concerning the location and characteristics of adult stem cells and the signals that wounded tissue produces to activate stem cells have increased our understanding of regeneration. Insulin-like growth factor 1 (IGF1) is an example of an important stem cell communication molecule. If the activity of the growth factor is experimentally enhanced, muscle regeneration improves.

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  • I wonder what is actually in the blood or serum she called it that helps the stem cells funcion, she was talking about aging.

    I also think about what causes the changes in older people's blood that reduce the ability for the stem cells to function. Im thinking its a hormone or something. Does any one have ideas? links to to learn more?

    thanx

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  • that is great, you art very kind to share these wonderful vidieos,hope you can find more and upload

  • great series! i love them! hope you can find more and upload it.

  • This is great, thanks for posting.

  • is growth factor not for building muscles, wats she talking about

  • Amazing stuff. Thanks for uploading these series. Can't believe no one has responded.

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