Roy Parker Part 1: mRNA Localization, Translation and Degradation
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Uploaded by ibioseminars on Jan 15, 2011
http://www.ibioseminars.org/index.php?option=com_content&view=article&...
Part 1
The control of mRNA production and function is a key aspect of the regulation of gene expression. In the first part of this lecture, I will discuss how in eukaryotic cells, the control of mRNA localization, translation and degradation in the cytoplasm allow for the proper regulation of the amount, duration, and location of protein production. The basic mechanisms of these processes are understood and reveal that the mechanisms of localization, translation, and degradation are interconnected. The unique properties of each mRNA are dictated by its intrinsic interactions with cellular machines, as well as its complement of mRNA specific RNA binding proteins and miRNAs. Strikingly, mRNPs are dynamic and can be modulated by protein modifications as well as by modification of the mRNA itself, thereby providing a diversity of targets for the regulation of mRNA function in response to extracellular signals.
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Sir
Is it possible that the videos be broken up into shorter parts. i.e., less than 30 minute parts?
Quantumash1 5 months ago
Thanks a lot Sir
This video is very helpful in understanding mRNA localization, translation and degradation.
Quantumash1 5 months ago