23andme Genetic Testing: a one year followup

https://www.23andme.com/
http://en.wikipedia.org/wiki/Single-nucleotide_polymorphism
http://www.snpedia.com/index.php/Promethease

Category:

Education

Tags:

• 23andme
• dna
• nerd
• genetics
• snp
• snpedia
• dtc
• science
• is
• fun

[Mushman34]

Also it's likely that snps and satellites favoured for ancestry assessment differ from those used for health assessment. This makes me doubt that they'd bother running the entirety of test as they would with the full package. It's likely they'd just select and amplify the regions of interest. Tracking ancestry usually involves using regions of highly variable and non selective mitochondrial DNA ensuring that any variation observed is the product of random mutations and not natural selection.

[zlyoga]

I do know for a fact that they run the same test for all versions. The company had confirmed this. Also this lets them have all the same data for the research they do on the site regardless of what version the person bought.

[Mushman34]

@zlyoga Hmm, that's a little sneaky. If I were to opt not to receive any information relating to health I'd like to think that they weren't going to compute and use that data for themselves. It's kind of getting to the point where we're able to find out things that we really shouldn't know. In a sense it allows for a kind of discrimination that goes beyond race, religion, age, or sex, but that is based on our fundamental nature. I don't really like it.

[zlyoga]

My point is though that it's not possible to separate it out. If a half identical region match with someone else gets found in the relative finder tool some of those snps may also be related to health traits, but you wouldn't be able to use that ancestry tool if they hadn't run that same data.

[Mushman34]

@zlyoga In my experience of relation and ancestry tests the areas used for comparison are largely non-coding for reasons that I stated previously with regards to mitochondrial DNA. My point being that it would be hard to extrapolate anything diagnostic of health issues from a nucleotide sequence that is not known to correspond to any particular gene. Then again, I am still an undergraduate. ;)

[zlyoga]

mitochondrial DNA though has limited usefulness. It only tells me about my mother mother etc. line. 23andme's ancestry tools have much greater depth than that because they look at more genetic information.

[BethaniBruised]

i think you are one of the most inspiring people ever

[bigjohn697791]

get to the point please

[iLOVENATURE2011]

nice video.,

[brendanmichaelpix]

Its worse than a real horoscope

[gm4ulkill]

holy shit wayyyyy toooooo much talking

[billhein0401]

This chick must have a genetic predisposition to moving her shoulders a lot.

[robinthestars]

teehee you're sooo cute and really brilliant! you make smart look pretty fucking cool.

[xBridget19x]

a reason i watched this whole thing is cause i think you are so freaking pretty. ha. dont be mad lol :(

[lakemarygardens]

The surveys are interesting but you know everyone is not going to be totally honest. The surveys made me yawn about half way through the questions so they might be good used as a sleep aid. LOL!

[DavidBGoodman]

Great video - I'm still deciding whether to get a 23andme account and this has been very helpful - thanks!