Mesenchymal stem cells and marrow stromal cells---2nd---

Marrow stromal cells
The existence of nonhematopoietic cells in bone marrow was first suggested by Cohnheim about 130 years ago [16]. To date, marrow stromal cells have been shown to differentiate into osteoblasts [17], chondrocytes [18], skeletal myocytes, adipocytes, and cardiomyocytes [19] in vitro, and thus are a useful cell source for regenerative medicine [20, 21]. Recent studies suggest that bone marrow stromal cells can also differentiate into a neuronal lineage [14], and murine bone marrow derived multipotent adult progenitor cell differentiate into dopaminergic neuronal cells [22]. Since the use of bone marrow stromal cells entails no ethical or immunological problems, and bone marrow aspiration is an established routine procedure, they may be a useful source of cells for transplantation.

Category:

Science & Technology

Tags:

• stem
• cell
• somatic
• regenerative
• medicine
• cell-based
• therapy