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The Bad Bug of P. Aer

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Uploaded by on Nov 24, 2009

A parody music video of The Fresh Prince of Bel Air - created for a medical school presentation about the bacteria Pseudomonas aeruginosa.

Lyrics:

Now this is a story all about how
my flora got twist turned upside down
And Id like to take a minute just sitting in class
To tell you how I became infected with Pseudomonas

In west edmontonia born and raised
In a hospital is where I spent most of my days
Chillin out back and relaxing all cool
Just waiting for the nurse to check out my stool

When a couple of bugs who were up to no good
Started making trouble in my neighbourhood
I got one small infection, my mom came quick
And said "let's hear it from this bug that's makin you sick"

Now, this is my story all about how
My genes got spread out all through the town
And I'd like you all to listen, just follow my lead
I'll tell you how I became this bad bug in his body

In every single corner of the world today
I'm in the soil, in the water, in your food it's okay
Cause I'm chillin' out maxin' relaxin' all cool
Till you get immunocompromised, then you're screwed

I'll give you skin infections and endocarditis
Maybe some UTI's and meningitis
The doc will ask you questions, take your history
And then she'll say "you got this bad bug in your body"

I adhered, replicated and madly proliferated
Your body tried to fight me but I simply evaded
I lysed all your cells with my exotoxin A
And don't forget my tricky little phospholipase

Right through your blood vessels I invaded
Bacteremia baby, now I'm disseminated
You better remember where my LPS is
If you're not careful, gonna give you sepsis!

Now you made it to the clinic 'bout seven or eight
And the doc wants my ID with a Gram stain
My microscopic rods they showed up light red
But size doesn't matter, at least that's what she said

I grow out on a plate and I smell quite fruity
But that doesn't mean I can't kick your booty
My kin up in the colonies are flat and round
But fluorescent microscopy will really nail me down

So your doc knows who I am but what she gonna do?
I got so much resistance that my Ohm's are through the roof
Hit me with the best, make your pharmacy proud
Just listen to my host as he breaks it all down

My doctor, yo, what was she thinkin?
Tryin to shoot me up with piperacillin
I told her I think that this bug is resistant
But the U of C doc no she just wouldnt listen

Yo doc, I think Im right
Im going into shock and my chest is all tight
This bug has an enzyme, the drug wont stay!
Hmmm, she said it might be beta-lactamase

I heard of pumps and further resistance
That throw these drugs right out of existence
I know of a new drug, well see how it fits in
I hope the bug is sensitive to tobramycin

I whistled for a nurse, and when she came near
I asked her "how does this drug work" I think I'm on the clear!
It binds the 30S ribosomal subunit
No more protein making, thats all there is to it

The doc pulled out my lab work and said it looks great
The drugs sent my Pseudomonas on its way
I rolled out of bed, went home with my ma
I was finally clear of P. aeruginosa

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  • Lol!!!!

  • Lmao, this is great. People don't know how hard it is to rhyme medical terms.

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