Renin Angiotensin System Explained
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Angiotensinogen -> angiotensin 1 -> angiotensin 2
renin catalyzes 1st reaction, acting in BLOODSTREAM.
2nd reaction is converted by ACE in LUNG.
Aside from its actions on AT1, ACE also breaks down bradykinin which is normally a local vasodilator (thus causing vasoconstriction)
AT2 actions:
1: thirst, SNS activation
2: Vasopressin (ADH) release
3: Direct vasoconstriction
4: Aldosterone activation
ACEi's inhibit all of these functions
5 months ago 4
All Comments (24)
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ACE is secreted by pulmonary and renal endothelial cells and catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II
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onlinemedicalpapers.blogspot.c
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Renin doesnt "turn into" angiotensin. Renin is responsible for converting the zymogen angiotensinogen into angiotensin I
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@jlgoedtel but he has taught this completely wrong
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@ArchonVideo lol...You'v got it....i caught on to this video instantly. Thanks man!
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@misterthilo at least somebody here knows what theyre talking about
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CORRECTIONS! Okay... I was a little tired making this one....
1. I mistakenly said "liver", it is the lungs (not the liver)
2. The correct spelling is not angiotension, angiotensin
NurseKGrant 4 months ago
You are correct about the Aldosterone. Many times the adrenal glads are simply referred to as part of the kidney. Remember.... Adrenal Cortex: Aldosterone, Cortisol, and the sex hormones. Adrenal Medulla: Epi, and NE. Thank you for pointing this out.
NurseKGrant 1 year ago