Imaging Antibodies In Vivo using Pre-clinical Small Animal Models; Opportunities and Challenges

Researchers routinely use antibodies to visualize protein expression in ex vivo and in vitro samples. Western blots and immunohistochemistry are the top two applications for utilizing these approaches. Antibodies are relatively amenable to chemical conjugation of fluorophores and radiotracers, and can be purchased as pre-labeled compounds. Given the widespread availability of high quality antibodies, why haven't they been used for in vivo research in a systematic way? In this webinar, we intended to highlight the challenges posed by utilizing antibodies in vivo, but also highlight key applications where antibodies can successfully be used in small animal models.

Category:

Science & Technology

Tags:

• antibodies
• protein expression
• Western blots
• immunohistochemistry
• fluorophores
• radiotracers
• small animal imaging
• molecular imaging
• in vivo imaging