Cells with clear endothelial morphology shown giving rise to blood cells. Left panel: phase contrast. Right panel: fluorescence detecting HIstone 2B-Venues expression.
!st pause in video: single mesodermal cell starting the colony
2nd pause: all cells in the colony exhibit a clear endothelial sheet mrophology
3rd pause: some cells lose tight integration into the endothelial sheet but keep adhering to endothelial cells
4th pause: Blood cells detach and are free-floating.
The arrow is following the starting cell and one daughter cell after each cell division until the end of the video
Timescale: days hours:minutes:seconds
Courtesy of Eilken et al.,
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