Von Willebrand Disease: Most Important Points

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Uploaded by on May 19, 2010

www.doctorpaul.org

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  • Type 1 : Autosomal dominant (Mild to moderately Reduced quantity of circulating vWF)

    Type 2: Has subtypes 2A is autosomal dominant (Defective multimer assembly)

    Type 3: Autosomal recessive (Extremely low levels of vWF)

  • Our younger son has this decease type 2. Thank you Dr Paul.

  • I am working on a sensor for electrochemical detection and quantification of Human vWF. Which is the best kind of Collagen that I could use as a substrate? type 1, 2, 3 or 4?

    Thank You very much!

    Tj

  • I have this disease. Thanks for the information.

  • thanks Dr. Paul

  • nice and smart. so helpful for my presentation

  • In Veterinary Medicine:

    on Wilebrand Disease: PT (WRI); PTT (WRI/INCREASED); FDPs (<10ug/mL); FIBRINOGEN (WRI)/ PLATELETS (WRI); BMBT (INCREASED)

    Three Types:

    Type I = decreased level of vWF:Antigen w/ all plasma multimers decreased (Welsh Corgi, Dobies, GSD, GRD,Poodle)

    Type II= decreased vWF:Antigen w/ decrease in HMW multimers (GSHP)

    Type III= undetectable levels of vWF:Ag (Scottish Terrier, Chesapeake Bay Retrievers, Shetland Sheepdog

  • hahaa this is funny

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