Autism & Genetic Disease

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Uploaded by on Jan 7, 2009

Barbara L. Trommer MD Pediatric Neurology .
Associate Director, Maimonides Developmental Center .
Medical School: Columbia University .
Fellowship: Children's Memorial Hospital Northwestern University Medical School
Pediatric Neurology

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Science & Technology

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  • Interesting to find you here (if 10 months ago), as I have just learned that Fragile X often use simultaneous, rather than sequential processing. I have always thought this of myself, my brother, and my autistic son, who it turns out, has a PTEN gene mutation. I wondered if the "science" that is "ABA" accounts for this difference.

    Knowing of my sons' genetic differences is not so i can cure or treat them. Just to understand them better (just one mom's opinion)

  • thanks for this..

  • If you mention drugs with Smith Lemli Opitz then you better have a research article I can read to have me believe it.

    But startle me with what they can do genetically.

  • I worked with a child diagnosed with autism with fused toes; now are you saying Smith Lemli Opitz Syndrome will have to be told to them also? What can they do genetically?

    Does the genetic information mean anything to parents yet or are we determining ways to abort?

    What can they do for genetic treatment of Smith Lemli Opitz Syndrome?

  • Autistic behaviors occur due to "stimulus selectivity" (SO - hereafter) regardless of genetic cause.

    Lovaas, Koegel, & Schreibman, (1979). SO in Autism: A Review of Research. Psy. Bulletin 86, 1236-1254.

    People learn in same way: classical conditioning (stimulus pairing) & operant conditioning (behavioral strengthening.

    Cook, Anderson, & Rincover (1987). SO & Stimulus Control: Problems & Strategies. In the book Educating & Understanding Autistic Children by Koegel, Rincover, & Egel.

  • I love this on two levels: controversial & true.

    Fragile X is merely the first autism to have a genetic cause known. Fragile X is a spectrum disorder like autism & when highly affected they get a co-morbid diagnosis which means they are just higher affected by mutation or chromosomal information lost until they don't fit in PDD-NOS as the genetic cause is known, but they sure are autistic in behaviors.

    Autism being behaviors & thus 1 day gone when all genetic causes known.

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