Uploaded by paulamaclaughlin on Aug 22, 2010
Courtesy of http://www.medstores.net - Patients talk about diagnosis and living with Parkinson's Disease.
Parkinson's disease (PD) is best described as a degenerative disorder of the central nervous system that often impairs the sufferer's motor skills, speech, and other functions.
Parkinson's disease belongs to a group of conditions called movement disorders. It is characterized by muscle rigidity, tremor, postural abnormalities, gait abnormalities, a slowing of physical movement (bradykinesia) and a loss of physical movement (akinesia) in extreme cases. The primary symptoms are the results of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine produced in the dopaminergic neurons of the midbrain (specifically the substantia nigra). Secondary symptoms may include high level cognitive dysfunction and subtle language problems. PD is both chronic and progressive.
PD is the most common cause of chronic progressive parkinsonism, a term which refers to the syndrome of tremor, rigidity, bradykinesia and postural instability. PD is also called "primary parkinsonism" or "idiopathic PD" (classically meaning having no known cause). While many forms of parkinsonism are idiopathic, "secondary" cases may result from toxicity most notably of drugs, head trauma, or other medical disorders. The disease is named after English apothecary James Parkinson, who made a detailed description of the disease in his essay: "An Essay on the Shaking Palsy" (1817).
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